Released on: September 8, 2008, 2:31 pm

Press Release Author: AnaSpec Inc.

Industry: Biotech

Press Release Summary: Expanding on its world-class collection of MOG peptides and
assay kits, AnaSpec is pleased to announce the release of 3 MOG recombinant
proteins, for human, mouse and rat.

Press Release Body: Sep 8, 2008

Expanding on its world-class collection of MOG peptides and assay kits, AnaSpec is
pleased to announce the release of 3 MOG recombinant proteins, for human, mouse and
rat.

These proteins, with sequences corresponding to human, mouse and rat extracellular
domain, together with a 6x His tag were expressed in E. coli and purified from urea
denatured bacterial lysate. The molecular weight found in all 3 recombinant proteins
was 14.23 kDa. The activity of these proteins was checked for their ability to
induce EAE in either mouse (for the human and mouse rMOGs) or rat (for rat rMOG).

About AnaSpec

AnaSpec is a leading provider of integrated proteomics solutions to the world’s
largest biotech, pharmaceutical, and academic research institutions. With a vision
for innovation through synergy, AnaSpec focuses on three core technologies:
peptides, detection reagents (including antibodies, dyes, and assay kits), and
combinatorial chemistry.

References:
1. Linares, D. et.al. Protein Expression and Purif. 34, 249 (2004).
2. Bettadapura, J. et.al. J. Neurochem. 70, 1593 (1998).
3. Oliver, AR. et al J. Immunol. 171, 462 (2003).
4. Von Budingen, H. et.al. J. Clin. Immunol. 21, 155 (2001).
5. Lyons, J. et.al. Eur. J. Immunol. 29, 3432 (1999)
6. Von Budingen, H. et.al. Eur. J. Immunol. 34, 2072 (2004).


Web Site: http://www.anaspec.com

Contact Details: AnaSpec Inc.
2149 O\'Toole Ave.
San Jose, CA 95131
1-408-452-5055 (Tel)
1-408-452-5059 (Fax)
1-800-452-5530
ping@anaspec.com
www.anaspec.com